Methyl fluoroacetate is an organic compound with the chemical formula C3H5FO2, highly toxic, is an important fluorinated organic compound, which has wide uses and good development prospects in dye, medicine, pesticide and other industrial fields.
Chemical Formula: C3H5FO2
Molecular weight: 92.069
Physicochemical properties
Density: 1.17g/cm3
Melting point: -45℃
Boiling point: 104℃
Flash point: 17.6℃
Vapor pressure: 0.000941mmHg at 25°C
Appearance: Colorless transparent liquid
Main Uses
Methyl fluoroacetate is an important fluorine-containing compound, which is widely used and developed in dye, medicine, pesticide and other industrial fields, and fluoroacetate is an important pharmaceutical intermediate in pharmaceutical industry, which is the starting material for preparing fluoropyrimidine antitumor drugs and fluoroquinolinic acid antibacterial drugs.
Storage and transportation
It shall be packed in sealed plastic barrel and stored in ventilated, dry and cool place. It is strictly prohibited to store and transport it with strong acid, strong alkali, strong oxidant and food. It shall be strictly managed and transported as highly toxic chemicals.
toxicity
Methyl fluoroacetate is a highly toxic chemical that can irritate the eyes, respiratory system and skin and is fatal upon contact. Fluoroacetic acid is flammable and can produce hydrogen fluoride gas, a toxic chemical, upon combustion.
Methyl fluoroacetate is hydrolyzed to generate fluoroacetic acid, which combines with coenzyme A of cell mitochondria to generate fluoroacetyl coenzyme A, and then combines with oxaloacetate to form fluorocitrate, which inhibits horsehead acid enzyme, accumulates citric acid in the body, blocks pyruvate metabolism, hinders normal oxidative phosphorylation process in the body, affects physiological metabolism of the body, and causes irreversible pathological changes in central nervous system, digestive system and cardiovascular system.
